Restylane Defyne Los Angeles, CA
What is it? | Benefits | Cost | Preparation | Procedure | Aftercare | Treatment Areas | Am I a Good Candidate? | Similar Procedures | Risks | Reviews | FAQs
Restylane® Defyne is a hyaluronic acid-based dermal filler designed to address deep lines and wrinkles while restoring volume to areas of the face affected by aging. This treatment smooths laugh lines, fills hollow temples, defines the cheeks and jawline, and corrects chin retrusion for a more balanced and youthful appearance.
As we age, our skin loses volume and elasticity, and collagen production slows, leading to thinner, less resilient skin. Restylane Defyne effectively counteracts these changes, delivering natural-looking results that rejuvenate your facial contours.
This innovative filler also addresses chin retrusion, where the chin recedes toward the neck, creating an unbalanced profile. By correcting chin retrusion, Restylane Defyne enhances the harmony between your face and neck, giving you a flattering, proportional side profile.
With its advanced formulation and life-changing capabilities, Restylane Defyne offers subtle, beautiful enhancements that help you look and feel your best.

What is Restylane Defyne?
Restylane® Defyne is a cutting-edge hyaluronic acid-based dermal filler specifically designed to address deep laugh lines (nasolabial folds and marionette lines) and correct chin retrusion. Hyaluronic acid is a naturally occurring substance in the body. It helps maintain a youthful and healthy complexion by restoring volume and moisture to the skin.

What sets Restylane Defyne apart is its XpresHAn Technology™, a unique gel formulation that smooths wrinkles and folds while preserving natural facial expressions and movement. This innovative filler provides subtle, long-lasting results that enhance your facial contours without compromising your ability to smile, laugh, or express yourself naturally.
Restylane Defyne Benefits
Restylane® Defyne offers a transformative solution for deep wrinkles, lines, and chin retrusion, providing natural-looking results with minimal downtime. This innovative filler helps restore facial balance and rejuvenates your appearance, making it an excellent option for patients seeking long-lasting improvements without surgery.
What Results to Expect:
- Smooths deep laugh lines, including nasolabial folds and marionette lines.
- Corrects chin retrusion, enhancing a balanced and desirable facial profile.
- Maintains natural facial expressions and movement for subtle, authentic results.
- Delivers a healthier, more youthful appearance.
How Long Will Results Last?
Results from Restylane Defyne typically last up to 12 months. Although the procedure provides temporary results, regular touch-ups are recommended to maintain the best results and a refreshed appearance.

Restylane Defyne Cost & Pricing Structure
The cost of Restylane® Defyne is determined by the number of syringes required to achieve your desired results. Additional charges may apply for touch-up sessions to maintain the optimal effect.
- US National Average: $650 per syringe
- Our Price: Costs vary depending on the provider. Please contact us for a personalized estimate.
- Additional Costs: None.
- Insurance: Cosmetic procedures like Restylane Defyne are typically not covered by insurance. However, we offer flexible payment options for your convenience.
Invest in a customized treatment plan to enhance your appearance with Restylane Defyne and achieve natural, lasting results.
Refine your look with Restylane Defyne at Spa26, designed to smooth wrinkles and restore youthful contours effortlessly
How the Procedure Works
Restylane® Defyne is a hyaluronic acid-based injectable treatment designed to smooth wrinkles, correct chin retrusion, and restore facial balance. Although non-surgical, proper preparation, aftercare, and recovery are essential for optimal results. Here’s what to expect:
Before & Preparation
During your consultation, your provider will discuss:
- Your medical history
- Contraindications and potential side effects
- Desired results
- Pre-treatment pictures for reference
Pre-procedure Guidelines:
- Avoid aspirin, NSAIDs, or blood-thinning medications to reduce the risk of bruising.
- Avoid alcohol and caffeine for at least 24 hours before your appointment.
- Plan your treatment at least two weeks before any significant events to allow for full recovery.


During the Procedure
Here’s what happens during your Restylane Defyne treatment:
- The treatment area will be cleansed to ensure it is free of makeup, dirt, or oils.
- A topical anesthetic will be applied to minimize discomfort.
- Injections are administered into the targeted areas, with adjustments made to achieve the desired results.
- Once the injections are complete, your provider may lightly massage the treated area to ensure the filler is evenly distributed and achieves a natural appearance.
Procedure Duration:
Most sessions last between 30 minutes to an hour, depending on the treatment area and complexity.
Aftercare & Recovery
Follow these aftercare instructions to promote a smooth recovery and enhance your results:
- Minimize strenuous activity and exposure to heat or sunlight for 24–48 hours.
- Use a cold compress to reduce swelling.
- Avoid washing the treated area for at least six hours post-procedure to allow the numbing agent to wear off.
- Refrain from taking aspirin, NSAIDs, or blood-thinning medications to minimize bruising.
- Any tenderness or swelling should subside within 1–2 weeks.
Your provider will offer personalized aftercare instructions to ensure you achieve the best possible outcome from your Restylane Defyne treatment.

Treatment Areas
Restylane® Defyne is a versatile dermal filler designed to enhance the lower portion of the face by addressing volume loss and smoothing wrinkles. Common treatment areas include:

- Laugh Lines: Smooths deep nasolabial folds and marionette lines for a rejuvenated appearance.
- Chin: Corrects chin retrusion, improving facial balance and enhancing the side profile.
These targeted areas make Restylane Defyne an effective solution for achieving a more youthful and proportional facial contour.
Choose Spa26 for Restylane Defyne to smooth deep wrinkles and restore natural contours with long-lasting, refined results
Am I a Good Candidate for Restylane Defyne?
Restylane® Defyne is suitable for individuals looking to smooth deep wrinkles, enhance facial contours, or correct chin retrusion. To determine if this treatment is right for you, consider the following criteria:
- Typical Age: 21 and older
- Weight: No weight restrictions
- Health Restrictions:
- Not recommended for individuals who are pregnant or breastfeeding.
- Avoid treatment if you have a history of severe allergic reactions (anaphylaxis).
- Not suitable for those with an allergy to lidocaine, a component of Restylane Defyne.
A consultation with an experienced provider is essential to assess your medical history, aesthetic goals, and suitability for Restylane Defyne.

Similar & Related Procedures
Below you can find procedures that are similar to Restylane Defyne:

- Botox®: Botox temporarily relaxes facial muscles by blocking nerve signals, reducing the appearance of dynamic wrinkles such as crow’s feet and frown lines.
- Juvederm®: A hyaluronic acid-based dermal filler that contours the face and smooths facial wrinkles. While effective, Juvederm typically lasts 6–9 months, offering shorter-lasting results compared to Restylane Defyne.
- Radiesse®: A unique dermal filler that not only smooths wrinkles but also stimulates collagen production for long-term improvement. Radiesse is ideal for lifting and contouring the face, with costs averaging $800 per syringe.
Each of these treatments has distinct features and benefits. Your provider can recommend the best option based on your specific aesthetic goals and facial anatomy.
Side Effects & Risks
While Restylane® Defyne is a safe and minimally invasive treatment, patients should be aware of potential side effects and risks to ensure a smooth and healthy recovery.
Common Side Effects:
- Itching
- Redness
- Bruising
- Swelling
- Pain or tenderness at the injection site
- Bump formation
Less Common Risks:
- Restricted blood flow
- Skin bumps
- Allergic reaction
- Infection
Most side effects are mild and resolve within a few days to a week. However, if you experience severe or prolonged symptoms, contact your provider immediately for further evaluation and care.

Restylane Defyne Reviews
Absolutely amazing experience every time. Been going here since January 2018, it’s now June 2018. Nazarian is a great doctor and she is truly an artist when it comes to fillers and botox!
Lili D.
Corvallis, OR
Loved coming into this office. I got fillers a couple of times, administered by Dr. Nazarian (SHE IS AMAZING!). I always get compliments from my friends and family. I definitely will continue coming back. Everyone says I look ten years younger! I also loved seeing Alex in the photo room, he is super funny and always makes my time there better :-)!
Pauline Z.
Los Angeles, CA
I came to Dr. Nazarian after contemplating getting fillers. She recommended a couple of options based on what I wanted and I couldn’t be happier! I was adamant that I wanted to just enhance my looks, not change them, and she did just that. The process was very professional and painless (which was surprising), and the whole office was welcoming. I am so happy with my face, and the best part is nobody knows I had anything done unless I tell them
Bethany C.
Palmdale, CA
Why Choose SPA26 for Restylane Defyne Dermal Fillers?
At SPA26, our priority is to provide you with the highest level of comfort and care for every procedure. Our team of experienced practitioners specializes in non-surgical treatments, including Restylane® Defyne, to help you achieve your aesthetic goals with safe and effective results.
We are dedicated to enhancing your natural beauty while boosting your confidence. Each treatment is tailored to your unique needs, ensuring results that look refreshed and natural.
With state-of-the-art facilities and a welcoming, professional environment, SPA26 offers a seamless experience from consultation to post-treatment care. Trust us to deliver personalized solutions that enhance your appearance and help you feel your best.
Spa26 offers Restylane Defyne to reduce deep lines and enhance facial harmony with natural movement and flexibility
Restylane Defyne FAQs
What should I avoid after Restylane Defyne injections?
After receiving Restylane® Defyne, it’s important to avoid sun exposure, strenuous activities, heat, and touching the treated areas for at least six hours. This helps reduce the risk of swelling, bruising, and infection.
How long does it take for Restylane Defyne to show results?
You will notice immediate improvements after your treatment. Full results typically develop within a week as the filler settles and any swelling subsides. Results can last up to 12 months, depending on individual factors.
Who should not use Restylane Defyne?
Restylane Defyne is not recommended for individuals who are pregnant or breastfeeding, have severe allergies (including anaphylaxis or allergies to lidocaine), are under 21 years of age, or are taking blood thinners or medications that prevent clotting. Consult your provider to determine if this treatment is suitable for you.
Can I sleep on my face after Restylane Defyne?
While there is no definitive evidence that sleeping positions affect fillers, it is advisable to sleep on your back for at least a week after treatment. This helps ensure the filler remains undisturbed during the initial settling period.
How long does swelling last after Restylane Defyne?
Mild swelling, bruising, tenderness, headache, and pain are common side effects that typically resolve within seven days post-treatment. Applying a cold compress can help reduce swelling.
Is it normal to have lumps after Restylane Defyne treatment?
Yes, experiencing small lumps or bumps after treatment is normal. These usually dissipate within a couple of weeks. If they persist, please contact your provider for evaluation.
Are financing options available?
Yes, at SPA26, we offer financing through third-party providers such as Care Credit and LendingUSA, both of which offer 0% interest for up to six months, making your treatment more accessible.
Where will my procedure be performed?
All treatments at SPA26 are conducted in our modern, comfortable treatment suites, ensuring a relaxing and professional experience.
What is SPA26's philosophy?
Our philosophy at SPA26 is to provide our patients with the most natural-looking results. We aim to enhance your appearance while helping you become the best version of yourself.
Will my medical insurance cover my procedure?
Cosmetic procedures like Restylane Defyne are elective and typically not covered by insurance. However, we offer flexible financing options through Care Credit and LendingUSA to accommodate your needs.
Are other providers available if I choose not to see Dr. Sheila Nazarian?
Yes, our team at SPA26 consists of highly trained and experienced practitioners who have been carefully selected and trained to ensure consistent techniques and excellent results.
Get soft, natural-looking results for deep folds and dynamic areas with Restylane Defyne at Spa26